Is life worth living? “It depends on the liver.” Thus did William James pose the question, as well as the “jocose” answer that was currently circulating, when he addressed the Harvard Young Men’s Christian Association in 1895. He then immediately put his audience on notice that his treatment of the question would not be jocular. “In the deepest heart of all of us there is a corner in which the ultimate mystery of things works sadly. . . . I ask you to join me in turning an attention, commonly too unwilling, to the profounder bass-note of life.”
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